Generic membrane-spanning features endow IRE1α with responsiveness to membrane aberrancy

Generic membrane-spanning features endow IRE1α with responsiveness to membrane aberrancy

Altered cellular lipid composition activates the endoplasmic reticulum unfolded protein response (UPR), and UPR signaling effects important changes in lipid metabolism. Secondary effects on protein folding homeostasis likely contribute to UPR activation, but deletion of the unfolded protein stress-sensing luminal domain of the UPR transducers PERK and IRE1α does not abolish their responsiveness...

Membrane-Spanning DNA Nanopores with Cytotoxic Effect**

DNA-based cytotoxic agents: Nanopores composed of folded DNA featuring a hydrophobic belt of ethyl phosphorothioate groups insert into bilayer membranes and kill cancer cells. The mode by which the pores achieve cell killing is elucidated with confocal microscopy.

A Generic Membrane Model (Note)

In this note we introduce a generic model for controlling migration in a network of distributed processes. To this end, we equip the membrane of a domain containing processes with some computing power, including in particular some specific primitives to manage the movements of entities from the inside to the outside of a domain, and conversely. We define a π-calculus instance of our model, and ...

Membrane reactors: A way to increase efficiency

Development of Membrane Bioreactor to Membrane Electro-bioreactor for Advanced Treatment of Wastewater

Limited available water resources have rendered wastewater reuse an important issue to specialists in most developed countries, today. The current study works on membrane filtration for treatment of industrial wastewater. By comparing the two methods of membrane bioreactor (MBR) and hybrid membrane electro bioreactor (MEBR) processes, it finds that earlier fouling in the membrane occurs in the ...